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In November, a 17-year-old boy was admitted to hospital for failed therapy of acute tonsillopharyngitis. The onset of disease was acute with a high temperature (up to 39.5°C), chill, fatigue and sore throat. His medical practitioner prescribed procaine penicillin i.m. once daily at dose of 0.6 MIU (600.000 IU) per 70 kg of body weight for three days. On examination, the patient was tired, with the axillary temperature of 38.8°C. The pharyngeal mucosa was red, the tonsils were hypertrophied, inflammed and inflammatory exudate formed yellow covering on their surfaces. Submandibular glands were also hypertrophied and tender. Other glands, including the liver and spleen, were intact and without any apparent changes.