Department of Dermatology and Venereology ****************************************************************************************** * ****************************************************************************************** Department of Dermatology and Venereology Faculty Hospital and Medical Faculty of Charles Hradec Králové is a workplace dealing with complex treatment of all diseases falling under dermatovenerology. In addition to providing quality curative and preventive care, it provi undergraduate and postgraduate education and continuous scientific activities. In the outp the clinic operates a general outpatient clinic (for adults and children) and specialised clinics (professional dermatosis clinic, venereological outpatient clinic, wound healing c dermatosis clinic, dark skin tumour clinic, dermatoscopic outpatient clinic, lymphology ou phototherapy, room for minor surgical excisions). In addition to the outpatient section, t inpatient section for both adult and paediatric patients. One of the current priorities of curative and preventive care is the analysis of the resul treatment in patients with psoriasis, atopic dermatitis, hidradenitis and chronic urticari of Dermatology and Venereology also focuses on the prevention, diagnosis and treatment of melanoma and non-melanoma skin tumours. In recent years, there have been significant devel healing and lymphology. Department of Dermatology and Venereology is equipped with a number of modern devices (e.g phototherapy, lymphology, dermatoscopy, participates in laser treatment, equipment for min procedures, including equipment for minor surgical excisions, etc.). Department of Dermatology and Venereology cooperates with many other departments and clini Králové University Hospital and the Faculty of Medicine of the Charles University in Hrade the framework of curative and preventive care. Close interdisciplinary cooperation include patients with autoimmune blistering dermatoses (cooperation with the Periodontology Depart Stomatology clinic), patients with allergies (cooperation with the Institute of Clinical I Allergy). In the treatment of skin cancer there is close cooperation with the Department o Radiotherapy and the Surgical Clinic (with the Department of Plastic Surgery) and with the of Otorhinolaryngology and Head and Neck Surgery. Cooperation with the Fingerland Institut continues in the field of dermatohistopathology. Another important area of cooperation wit and Urology Clinic (and with the Hradec Králové Public Health Service) is the epidemiologi sexually transmitted diseases and the provision of the widest possible range of modern dia in the system of "surveillance" of these diseases. The clinic has the status of an accredited department with the possibility of further trai and thus provides the possibility of preparing residents for certification with profession theoretically and practically. Continuous scientific activities are carried out in the field of science and research. Wit of research, cooperation is established with other disciplines and clinics at the Hradec K Medicine and Hospital (Institute of Clinical Immunology and Allergy, Institute of Clinical Diagnostics, Institute of Preventive Medicine), as well as with the Technical University o Research activities are carried out with the support of the Cooperatio project,of Charles internal projects are submitted within the Faculty Hospital. For the strategic development efforts are made to obtain the status of an accredited department for the possibility of d in the field of dermatovenerology. Department of Dermatology and Venereology organises professional seminars for doctors in t dermatovenerology (3 - 4 times a year) and from 2023 organises a national event Hradec Der Days (once a year). In addition, it is also a traditional professional guarantor and organ dermatovenerology events such as conferences in Lipová and others. Physicians of the clinic publish in Czech and international journals, participate in domes activities and lecture at domestic and international events (congresses of the European Ac Dermatovenerology, congresses of Czech-Slovak Dermatology, National Dermatology Congresses seminars, from 2023 the Hradec Days congress, etc.). In recent years, physicians have also contributed to a number of textbooks (Salavec - Clin Dermatovenerology, volumes 1 and 2; Differential Diagnosis in Dermatovenerology; Ocular Ma Systemic Diseases - Salavec, Bartlová). They repeatedly prepare teaching scripts in dermat they are authors of textbooks and monographs (Ettler, Bělobrádek, Salavec). Some of doctor investigators or co-investigators of grant projects (Ettler, Čelakovská) and authors of pu with impact factor (Čelakovská, Ettler, Salavec, Hamáková and others). Doctors of the clin investigators of international clinical trials in the field of psoriasis and atopic dermat ****************************************************************************************** * Main research topics ****************************************************************************************** • doc. MUDr. Jarmila Čelakovská, Ph.D. [ URL "https://is.cuni.cz/webapps/whois2/osoba/1544 lang=en"] - Examination of specific IgE by molecular component diagnostics in patients w dermatitis. The significance of food allergy in patients with atopic dermatitis. (cooper Institute of Clinical Immunology and Allergy of Medical Faculty and Faculty Hospital Hra • doc. MUDr. Jarmila Čelakovská, Ph.D. - Investigation of the immunological profile in pat atopic dermatitis. Immunophenotyping by flow cytometry, evaluation of surface CD markers interleukin levels (cooperation with the Institute of Clinical Immunology and Allergy Me and Faculty Hospital Hradec Králové). • MUDr. Simona Vachatová, Ph.D. [ URL "https://is.cuni.cz/webapps/whois2/osoba/14722291925 - Influence of metabolic syndrome on biological age in patients with psoriasis (collabor Institute of Preventive Medicine of Medical Faculty Hradec Králové) • MUDr. Květoslava Hamáková-Monitoring cardiovascular risks in patients with psoriasis (co the Institute of Preventive Medicine of Medical Faculty Hradec Králové) • doc. MUDr. Jarmila Čelakovská, Ph.D., MUDr. Simona Vachatová, Ph.D, MUDr. Lenka Čáková – DNA methylation changes and other biomarkers in patients with cutaneous melanoma. (colla the Institute of Clinical Biochemistry and Diagnostics of Medical Faculty and Faculty Ho Králové) • doc. MUDr. Karel Ettler, CSc. [ URL "https://is.cuni.cz/webapps/whois2/osoba/18442757188 lang=en"] , MUDr. Veronika Wertzová Ph.D. - Research and development of special textiles in emergency and crisis situations "TexPrevent" - creation of textile garments for patie eczema (especially children). ****************************************************************************************** * Scientific research groups ****************************************************************************************** • doc. MUDr. Jarmila Čelakovská, Ph.D. - cooperates with the Institute of Clinical Immunol of Medical Faculty and Faculty Hospital Hradec Králové (prof. Ctirad Andrýs, prof. Jan K Ing. Petra Boudková) • doc. MUDr. Karel Ettler, CSc., MUDr. Veronika Wertzová, Mgr. Libuše Ježková. – "Textiles - cooperates with the Technical University in Liberec and VÚB (Institute of Cotton Resea Ústí nad Orlicí. • MUDr. Květoslava Hamáková, prof. MUDr. Lenka Borská, Ph.D., MUDr. Simona Vachatová, Ph.D cardiovascular risks in patients with psoriasis (collaboration with the Institute of Pre of Medical Faculty Hradec Králové) • doc. MUDr. Jarmila Čelakovská, Ph.D., MUDr. Lenka Čáková, MUDr. Simona Vachatová, Ph.D. with the Institute of Clinical Biochemistry and Diagnostics of Medical Faculty and Facul Hradec Králové (cooperation with PhDr. Petra Šauer Mikysková) ****************************************************************************************** * Equipment ****************************************************************************************** • Spectrophotometer in the UV and visible region • Solar radiation simulator • Phototherapy devices for local and whole-body treatment • Equipment for the operating theatre: cryocutters, electrocautery, basic surgical equipme • Handheld and digital dermatoscopes • Iontophoresis device • Devices for lymphology ****************************************************************************************** * Cooperation ****************************************************************************************** • Technical University in Liberec, VÚB (Institute of Cotton Research) Ústí nad Orlicí, VÚB Cotton Research) a. s. Ústí nad Labem-research team in TAČR (Technology Agency of Czech MPO (Ministry of Trade and Industry) • Department of Dermatology and Venereology, Medical Faculty and Faculty Hospital in Plzeň Čelakovská, Komorousová Michaela, Cetkovská Petra, Novák Martin, Čermáková Eva, Bukač Jo Ctirad & Salavec Miloslav (2021) Dermatitis herpetiformis Duhring - evaluation of diseas tissue transglutaminase levels in 122 patients on dapsone therapy, Food and Agricultural 32:1, 237-252, DOI: 10.1080/09540105.2021.1918067 ****************************************************************************************** * International cooperation ****************************************************************************************** • doc. MUDr. Jarmila Čelakovská-Observational study Globostad OBS15990 • Piergiacomo Calzavara-Pinton, Jarmila Čelakovská, Hilde Lapeere, Gregor Holzer, Mona Al- Chu, Jiangming Wu, Marius Ardeleanu, Kwinten Bosman. Baseline demographics, comorbiditie burden in patients with atopic dermatitis: An update from the GLOBOSTAD observational st Volume 78, Page 136-136, Supplement 112, Special Issue, SI Meeting Abstract 000385.Publi December 2023 • Calzavara-Pinton, P., Čelakovská, J., Lapeere, H. et al. Baseline Demographics, Comorbid Patterns and Burden of Atopic Dermatitis in Adults and Adolescents from the GLOBOSTAD Lo Observational Study. Adv Ther 40, 5366–5382 (2023). https://doi.org/10.1007/s12325-023-0 • Piergiacomo Calzavara-Pinton, Jarmila Čelakovská, Hilde Lapeere, Gregor Holzer, Mona Al- Chu, Jiangming Wu, Marius Ardeleanu, Kwinten Bosman. Baseline demographics and family di patients with atopic dermatitis: an update from the GLOBOSTAD registry. British Journal Volume 188, Issue Supplement_2, February 2023, ljac140.028, https://doi.org/10.1093/bjd/ • Published: 25 January 2023 • Calzavara-Pinton, P (Calzavara-Pinton, Piergiacomo) ; Čelakovska, J (Celakovska, Jarmila H (lapeere, HilDe) ; Al-Ahmad, M (Al-Ahmad, Mona) ; Chu, CY (Chu, Chia-Yu) ; Wu, JM (Wu, Ardeleanu, M (Ardeleanu, Marius), Ozturk, ZE (Ozturk, Zafer E. Baseline patient demograp comorbidities in patients with atopic dermatitis from the GLOBOSTAD registry. British Jo Dermatology; 187, 3, E 110-111. Meeting abstract 224, Published 2022 • Calzavara-Pinton, P (Calzavara-Pinton, Piergiacomo); Celakovska, J (Celakovska, Jarmila) (Lapeere, Hilde). Baseline patient demographics and comorbidities in patients with atopi from the GLOBOSTAD registry. Journal of the American Academy of Dermatology, Volume 87, AB23-AB23, Supplement, S, Meeting Abstract 34329, Published SEP 2022, Indexed. 2023-02-0 Type, Meeting Abstract • Calzavara-Pinton, P (Calzavara-Pinton, Piergiacomo); Celakovska, J (Celakovska, Jarmila) (Lapeere, Hilde).Baseline Demographics and Comorbidities in Patients With Atopic Dermati From the GLOBOSTAD Registry. Journal of the American Academy of Dermatology, Volume 89, AB127-AB127, Supplement S, Meeting Abstract 42253 • Doc. Ettler – Representation in international organizations that govern the field: the E Dermatology Forum (EDF), UEMS-EBDV (UEMS-European Committee for Dermatovenerology)