Department of Oncology and Radiotherapy ****************************************************************************************** * ****************************************************************************************** The Department of Oncology and Radiotherapy is an important oncological workplace in the w Republic. It is the main workplace providing care in the fields of clinical oncology and r in the Hradec Králové Region, it is the leading workplace of the Comprehensive Oncology Ce University Hospital Hradec Králové, it is responsible for the coordination of oncological the regional oncology group of the Hradec Králové Region. From the professional point of v provides specialised and highly specialised care in clinical and radiation oncology for pa Hradec Králové Region, for some rare diseases and specialised treatment techniques for oth Specialists from the clinic are invited to national expert committees and boards within th clinical oncology, radiation oncology and palliative medicine. The experience from the app some therapeutic methods, which were first introduced at the clinic in the Czech Republic modified, is transferred to other departments. In addition to medical activities, the clinic provides teaching activities within the Facu in Hradec Králové, namely undergraduate, postgraduate and specialisation training, and sci activities. Scientific research activities include preclinical research and academic clinical trials i areas: • Predictive and prognostic factors in cancer treatment • Modern methods of anti-cancer systemic therapy • Modern techniques of external radiotherapy and brachytherapy • Supportive and palliative care He is currently the investigator or co-investigator on three AZV grants and the principal on one "investigator-initiated" study. Publication outputs over the last 5 years (2019-202 37 peer-reviewed articles, of which 20 have been published in impact factor journals. The investigator or co-investigator of 4 AZV grants and one AZV junior project. ****************************************************************************************** * Main research topics ****************************************************************************************** • Predictive and prognostic factors in cancer treatment • Modern techniques of external beam radiotherapy and brachytherapy • Supportive and palliative care ****************************************************************************************** * Scientific research groups ****************************************************************************************** • Predictive and prognostic factors in cancer treatment (Doc. MUDr. Milan Vošmik, Ph.D. [ is.cuni.cz/webapps/whois2/osoba/1298309806598448/?lang=en"] , MUDr. Jindřich Kopecký, Ph "https://is.cuni.cz/webapps/whois2/osoba/1459259820082972/?lang=en"] , MUDr. Ondřej Kube "https://is.cuni.cz/webapps/whois2/osoba/1659447893762955/?lang=en"] .) • Modern techniques of external beam radiotherapy and brachytherapy (Prof. MUDr. Jiří Pete "https://is.cuni.cz/webapps/whois2/osoba/1382558754094498/?lang=en"] , Doc. MUDr. Igor S [ URL "https://is.cuni.cz/webapps/whois2/osoba/1490968794529870/?lang=en"] ) • Supportive and palliative care (Prof. MUDr. Stanislav Filip, Ph.D., DSc. [ URL "https:// webapps/whois2/osoba/1979497732033475/?lang=en"] ) ****************************************************************************************** * Equipment ****************************************************************************************** • Three Varian TrueBeam linear accelerators (Varian, Palo Alto, California, USA) • Afterloading brachytherapy device GammaMed iX • Sonotherm hyperthermia ****************************************************************************************** * Achievements ****************************************************************************************** • Introduction of the whole-body irradiation technique before horizontal hematopoietic ste transplantation • Clinical applications of accelerated partial breast irradiation using the interstitial b technique • Organization and implementation of the CA209-9KH clinical trial (investigator initiated The department is a member of the CZECRIN ONCO academic research network and international research groups, such as the European Organisation for Research and Treatment of Cancer an European Cooperative Oncology Group. Specialists from the clinic are members of national a expert committees and boards in the fields of clinical oncology, radiation oncology and pa medicine.