Mazanek, Pavel
Poslední změna: 19.09. 2016

Department of Clinical Immunology and Allergology

We provide the teaching of immunology in the context of both the Czech language and English language master‘s degree program in General Medicine and in Dentistry at the Charles University Faculty of Medicine in Hradec Králové. We are accredited for doctoral study in medical immunology, habilitation, and nomination proceedings for professorship candidates. Our department is a training center for doctors serving in allergology and clinical immunology. We have also implemented internships in clinical laboratories and internships in biomedical study programs at the Charles University Faculty of Pharmacy and the University of Pardubice.

Clinical and laboratory diagnostics of immune disorders

We provide diagnostic and therapeutic care to patients with allergic diseases and disorders of the immune system. We apply functional diagnostics for this purpose. In our clinical lab we have at our disposal all laboratory procedures necessary for the diagnostic decision of doctors of all disciplines. The main technology is multicolor flow cytometry and various immunochemical methods, mainly ELISA, immunofluorescence, immunoblot, and the newly introduced Luminex technology. We cultivate and analyze cell cultures for diagnostic and research purposes.

All about inflammation

The Department of Clinical Immunology and Allergology at the Charles University Faculty of Medicine and University Hospital has from the very beginning been as an academic workplace focused on research. Research programs have been implemented that investigate autoimmune and injurious inflammation. Particular attention is paid to allergic inflammation. We study the dynamics of inflammatory response following cardiac surgery in cooperation with the Department of Cardiac Surgery and with the University Hospital. Together with experts from the Department of Obstetrics and Gynecology, we have looked into the proportion of inflammation on the pathogenesis of premature rupture of the fetal membranes. Our initial findings have already been published. We are also involved in research concerning topics from a variety of clinics at the University Hospital. For example, we are involved in the long term research projects that investigate immunity affected by aphaeretic procedures in hemato-oncology, injurious inflammation in rheumatology, gastroenterology, dentistry, dermatology and infectious medicine.