Mazanek, Pavel
Poslední změna: 19.09. 2016

Department of Clinical Microbiology

We teach medical microbiology in the master´s program for students of General Medicine and Dentistry and for bachelor‘s degree students in the General Nursing program. We emphasize the practical aspects of the field, i.e. the possibilities of microbiological diagnostics and its indications, the evaluation and interpretation of the clinical significance of microbiological findings, the evaluation of antibiograms and indications of antibiotics in relation to antibiotic resistance. Students learn the basic techniques of microbiological diagnosis – microscopy, culturing, and serology in clinical teaching. Students of general medicine can deepen their knowledge in the optional Clinical Microbiology course, which investigates in detail the topics of the rational use of antibiotics, antibiotic resistance and infections associated with health care. For foreign students, we offer an optional subject entitled Microbiological Aspects of Tropical Infectious Diseases. We regularly organize regional scientific workshops on various topics of clinical microbiology for doctors and lab technicians at the University Hospital and other medical facilities of Eastern Bohemia. The ATB center annually takes part in the European Antibiotic Awareness Day, a campaign to promote responsible use of antibiotics.

Revealing microscopic pests

Concerning diagnostic care, our institute provides comprehensive services in the field of medical microbiology (bacteriology, virology, mycology, parasitology) and at the same time functions as an independent antibiotic center and national reference laboratory for cytomegaloviruses. In cooperation with the Clinic of Biochemistry and Diagnostics, molecular-biological diagnostics is provided mainly in the fields of virology, mycology, and mycobacteriology. Staff at the Laboratory of Bacteriology and Mycology, in addition to routine diagnostics, deal with selected special diagnostics of infectious complications of ICU patients, patients in immunosupression, patients with infections of the bloodstream, the CNS, bones, joints, and mycobacterial infections. A major activity of our laboratories is microbiological control of the hospital environment, sterility of equipment, cells, and tissues used for treatment. The antibiotic center systematically monitors antibiotic resistance and is involved in the European Antimicrobial Resistance Surveillance Network (EARS-Net, ECDC, Stockholm).

Examining the effectiveness of new substances

Currently, our research focuses mainly on the area of the mycology and pharmacology. In cooperation with the Faculty of Pharmacy, we research and evaluate the antimicrobial effect of newly synthesized substances. Also significant is our cooperation with the Faculty of Military Health at the University of Defense. In addition, we cooperate with the scientific workplace in Techonín on the topic of laboratory diagnostics of dangerous infections. In cooperation with the staff of the 2nd Internal Clinic of the Teaching Hospital, we have been engaged for several years in research into intestinal bacterial microflora in idiopathic inflammation and colorectal neoplasia and Helicobacter pylori infection in experimental models.