Mazanek, Pavel
Poslední změna: 05.02. 2021

Department of Pathological Physiology

In the curriculum of General Medicine at our Faculty, pathophysiology comprises 157 instruction hours in the 3rd study year before students move on to clinical coursework in the fourth year. Pathophysiology is quite unique as it does not have to introduce many new facts but has to teach (force!) the students to integrate their theoretical knowledge to understand the origins (etiology) and development (pathogenesis) of diseases so that those diseases (or their complications) may be prevented or adequately treated. In our instruction a comprehensive (global, holistic) approach is maximally applied to help students understand the basics of the disease. Such an approach is often mistakenly considered to be the exclusive domain of alternative / complementary medicine. Pathophysiology is a field that can be very unpleasant for students who are accustomed mainly to memorizing facts. However, it is always better for the patient if the doctor does not mechanically apply the “best clinical practices“ (guidelines). During the final oral exam, students are evaluated not only in terms of their knowledge but also in terms of how trustworthy they would seem to be as doctors.

Electrophysiology of vision and CNS

Research in Electrophysiological laboratories represents at present due to momentary personal cast the only research orientation of the Department of pathological physiology and scientific activities take place in tight collaboration with Department of Biophysics. This research (founded 50 years ago by prof. Jaroslav Peregrin) is oriented toward development of new variants of visual evoked potentials (VEPs) and cognitive brain potentials mainly to various types of motion stimulations and their clinical applications. Long termed systemic work in this field resulted in obtaining three patents that were practically realized in the form of prototypes of the “Mobile device for VEP examination”. This device should extend the diagnostic VEP method also outside specialized laboratories. For the development of this device, we obtained the Marmor award from the International Society for Clinical Electrophysiology of Vision (ISCEV). Activities of this research are supported by Czech and international grants.

 

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