The subject of pathological anatomy is one of the most extensive in the medical curriculum. In the early years of the faculty, lectures in pathological anatomy were given solely by Professor Fingerland; it had generally been a privilege of heads. Currently, there are a total of five pathology courses amounting to a total of 492 teaching hours of lectures and 705 hours of practicals. In addition to the teaching of its own compulsory subject, the department is involved in the teaching of several elective interdisciplinary courses, e.g. Clinico-Pathological Conferences, Selected Chapters in Endocrinology and Manifestations of Systemic Disorders in the Oral Cavity. The classes take place in a modernized auditorium with 120 seats and in a microscope lecture room with 36 seats equipped with video-microscopes and monitors. Since 2006, an online digital atlas collection of histopathology specimens has been available to students.
Finding the final diagnosis
The main objective of the department’s activities includes a description of complex diagnostic surgical pathology cases, including intraoperative frozen sections, cytology (both gynecological and non-gynecological), and autopsy diagnostics for all clinical departments of the University Hospital as well as for the regional hospitals. Our department is an important consultation center, collaborating closely with a number of hospitals in the Czech Republic and Slovakia. Our facilities and skilled team of employees (consultants, medical scientists and laboratory technicians) ensure the most accurate biopsy diagnosis. We use both classic and modern laboratory techniques, such as immunohistochemistry, histochemistry, immunofluorescence, electron microscopy, molecular pathology, computer image analysis, as well as telepathology and virtual digital microscopy.
Currently, we cover the entire spectrum of routine and research methods used in pathology – from autopsy diagnosis through surgical pathology and cytology, including gyneco-cytological screening. Our laboratory uses many modern diagnostic tools and equipment – electron microscopy, direct and indirect immunofluorescence, a wide spectrum of immunohistochemical methods, in situ hybridization techniques, PCR diagnostics as well as next generation sequencing. With the introduction of modern technology, the department has begun to carry out experiments on tumor cell lines. The department has become a reference laboratory for the predictive diagnosis of cancer.